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NEW QUESTION: 1
A 55-year-old female is receiving chemotherapy for metastatic carcinoma. She threatens to stop her treatment because of severe nausea and vomiting. The oncologist plans to use prochlorperazine to reduce the nausea and vomiting associated with chemotherapeutic agents. What is the mechanism of action of prochlorperazine?
A. Cannabinoids related
B. Blocking dopamine receptors
C. H2 receptor antagonist
D. Serotonin 5-HT3 antagonist
E. Blockage of prostaglandins
Answer: B
Explanation:
Explanation
B: A variety of drugs have been found to be of some value in the prevention and treatment of vomiting, especially cancer chemotherapy-induced vomiting. With the exception of thioridazine, most of the neuroleptic drugs have antiemetic effects that are mediated by blocking D2 dopaminergic receptors of the chemoreceptor trigger zone of the medulla. Phenothiazines, such as prochlorperazine, were the first drugs shown to be effective antiemetic agents and act by blocking dopamine receptors. They are effective against low to moderately emetogenic chemotherapeutic agents (for example, fluorouracil and doxorubicin). Although increasing the dose improves antiemetic activity, side effects, including hypotension and restlessness, are dose limiting. Other adverse reactions include extrapyramidal symptom and sedation. A: Serotonin 5-HT3 antagonist is incorrect. The specific antagonists of the 5-HT3 receptor, ondansetron and granisetron, selectively block 5-HT3 receptors in the periphery and in the brain (chemoreceptor trigger zone). C:
Cannabinoids related is incorrect. Cannabinoids are marijuana derivatives including dronabinol and nabilone and are effective against moderately emetogenic chemotherapy. However, they are seldom first-line antiemetics because of serious side effects. D: Blockage of prostaglandins is incorrect. Dexamethasone and methylprednisolone used alone are effective against mildly to moderately emetogenic chemotherapy. Their antiemetic mechanism is not known, but it may involve blockade of prostaglandins. E: H2 receptor antagonist is incorrect. Antagonists of histamine H2 receptor block the action of histamine at all H2 receptors; their chief clinical use is as inhibitors of gastric acid secretion.

NEW QUESTION: 2
DRAG DROP

Answer:
Explanation:

NEW QUESTION: 3
PAN_OSバージョン9.1以降、セキュリティポリシールールのユーザーフィールド内での使用がサポートされている新しいタイプのオブジェクトはどれですか。
A. 動的ユーザーグループ
B. リモートユーザー名
C. ローカルユーザー名
D. 静的ユーザーグループ
Answer: A

NEW QUESTION: 4
Ein Systemadministrator meldet, dass einer der beiden Domain Name Server nicht auf DNS-Anfragen von Clients zu reagieren scheint. Die Server sind betriebsbereit, der Namensdienst wird auf ihnen ausgeführt und DNS-Anforderungen werden in den Protokollen angezeigt. Beide Server antworten auf Warteschlangen an der Konsole. Welches der folgenden Tools sollte der Systemadministrator verwenden, um weitere Informationen zu sammeln?
A. Generieren Sie DNS-Abfragen und verwenden Sie einen Paket-Sniffer, um den DNS-Verkehr zu / von beiden Nameservern zu erfassen und nach Unterschieden zu suchen.
B. Pingen Sie die Nameserver nach IP-Adresse, um sicherzustellen, dass sie aktiv sind, und pingen Sie dann jeden Nameserver nach Namen, falls die Namensauflösung für die Servernamen nicht funktioniert.
C. Führen Sie tracert von einem Desktop-Client aus, um jeden Nameserver abzufragen und festzustellen, welche Antworten von jedem Server zurückgesendet werden.
D. Führen Sie auf jedem Nameserver einen Port-Scanner aus, um sicherzustellen, dass der TCP-Port 53 geöffnet ist und überwacht.
Answer: A